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Except for patient age, clinicopathologic factors as well as disease-free survival were not significantly different between the OSO group and the TSO group in the aforementioned cancer stages. Cribriform adenocarcinoma of the tongue and minor salivary gland: transoral robotic surgical resection. Cribriform adenocarcinoma of the tongue and minor salivary gland CATMSG is a rare, locally invasive, and poorly recognized tumor, typically occurring on the base of the tongue.

This case report describes the previously unreported use of transoral robotic surgery TORS for the local resection of CATMSG in a novel location, the palatine tonsil, and leverages follow-up information to compare TORS to conventional surgical approaches. We performed transoral radical tonsillectomy, limited pharyngectomy, and base-of-tongue resection with staged left selective neck dissection.

Tumor pathology revealed an infiltrating salivary gland carcinoma with perineural invasion and a histologically similar adenocarcinoma in 1 of 64 left neck lymph nodes. TORS was performed with no perioperative complications, and the patient was subsequently discharge on postoperative day 3 with a Dobhoff tube. Postoperatively, the Dobhoff tube was removed at 1 month, the patient was advanced to soft foods by mouth at 2 months, and 3-month positron emission tomography-computed tomography scan showed no evidence of distant metastases and evolving postsurgical changes in the left tonsillectomy bed.

Applied Physiology, Nutrition, and Metabolism

This case report highlights the use of TORS resection with minimal acute and long-term morbidity compared to conventional approaches for the resection of this rare, locally invasive salivary gland carcinoma in the palatine tonsil. Karger AG, Basel. Surgical resection of duodenal lymphangiectasia: A case report. PubMed Central. Intestinal lymphangiectasia, characterized by dilatation of intestinal lacteals, is rare. The major treatment for primary intestinal lymphangiectasia is dietary modification.

Surgery to relieve symptoms and to clarify the etiology should be considered when medical treatment failed.

This article reports a year-old woman of solitary duodenal lymphangiectasia, who presented with epigastralgia and anemia. Her symptoms persisted with medical treatment. Surgery was finally performed to relieve the symptoms and to exclude the existence of underlying etiologies, with satisfactory effect. In conclusion, duodenal lymphangiectasia can present clinically as epigastralgia and chronic blood loss. Surgical resection may be resorted to relieve pain, control bleeding, and exclude underlying diseases in some patients.

Postoperative digestive function after radical versus conservative surgical philosophy for deep endometriosis infiltrating the rectum. To compare delayed digestive outcomes in women managed by two different surgical philosophies: a radical approach mainly related to colorectal resection , and a conservative approach involving rectal shaving and rectal nodule excision. University tertiary referral center. Seventy-five patients managed by surgery for deep endometriosis infiltrating the rectum. Twenty-four women were managed during a period when surgeons pursued a radical philosophy toward treatment, and 51 women were managed during a period when a conservative philosophy was adopted.

Preoperative patient characteristics, rectal nodule features, and associated localizations of the disease were comparable between the two groups. It seems that reducing the rate of colorectal resection leads to better functional outcomes in women presenting with rectal endometriosis, lending support to the conservative surgical philosophy over mandatory colorectal resection.

Published by Elsevier Inc. All rights. Hilar cholangiocarcinoma: controversies on the extent of surgical resection aiming at cure. Hilar cholangiocarcinoma is the most common malignant tumor affecting the extrahepatic bile duct. Surgical treatment offers the only possibility of cure, and it requires removal of all tumoral tissues with adequate resection margins. The aims of this review are to summarize the findings and to discuss the controversies on the extent of surgical resection aiming at cure for hilar cholangiocarcinoma.

The English medical literatures on hilar cholangiocarcinoma were studied to review on the relevance of adequate resection margins, routine caudate lobe resection , extent of liver resection , and combined vascular resection on perioperative and long-term survival outcomes of patients with resectable hilar cholangiocarcinoma. Complete resection of tumor represents the most important prognostic factor of long-term survival for hilar cholangiocarcinoma.

The primary aim of surgery is to achieve R0 resection. When R1 resection is shown intraoperatively, further resection is recommended. Routine caudate lobe resection is also advocated for cure. The extent of hepatic resection remains controversial. Most surgeons recommend major hepatic resection. However, minor hepatic resection has also been advocated in most patients.

The decision to carry out right- or left-sided hepatectomy is made according to the predominant site of the lesion. Portal vein resection should be considered when its involvement by tumor is suspected. The curative treatment of hilar cholangiocarcinoma remains challenging. Advances in hepatobiliary techniques have improved the perioperative and long-term survival outcomes of this tumor. Objective: To clarify whether the surgical treatment for hilar cholangiocarcinoma combined with artery reconstruction is optimistic to the patients with hilar cholangiocarcinoma with hepatic artery invasion.

Methods: There were patients who received treatment in the First Affiliated Hospital to Army Medical University from January to January analyzed retrospectively. There were 27 patients underwent palliative operation, patients underwent radical operation, radical resection account for General information of patients who underwent radical operation treatment was analyzed by chi-square test and analysis of variance. The period of operation time, blood loss, the length of hospital stay and hospitalization expenses of the radical operation patients were analyzed by one-way ANOVA.

Comparison among groups was analyzed by LSD- t test. Results: The follow-up ended up in June first, Each of patients followed for 6 to 60 months, the median follow-up period was 24 months. And 1-, 3-, and 5-year survival rates of hepatic artery reconstruction group was lower than routine radical group and portal vein reconstruction group significantly P radical operation group and the portal vein reconstruction group were The data shows that the.

Mutations in TP53 are a prognostic factor in colorectal hepatic metastases undergoing surgical resection.

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The aim of this study was to analyze the prognostic value of TP53 mutations in a consecutive series of patients with hepatic metastases HMs from colorectal cancer undergoing surgical resection. Ninety-one patients with liver metastases from colorectal carcinoma were included.

Mutational analysis of TP53, exons , was performed by single-strand conformation polymorphism and sequencing. P53 and P21 protein immunostaining was assessed. Multivariate Cox models were adjusted for gender, number of metastasis, resection margin, presence of TP53 mutations and chemotherapy treatment. Forty-six of 91 P53 and P21 protein immunostaining did not show correlation with survival.

TP53 mutational status seems to be an important prognostic factor in patients undergoing surgical resection of colorectal cancer HMs. Free radical oxidation in rat myocardial homogenate was studied by chemiluminescent assay during the early terms after maximum permissible liver resection. During this period, activation of free radical oxidation was biphasic.

The critical terms characterized by dramatic intensification of free radical oxidation in the myocardium are the first hour and the first day after surgery. The period from 3 to 12 h after surgery, in which the indices of chemiluminescence decrease, can be tentatively termed as the period of "putative wellbeing". Normalization of the free radical oxidation processes in the myocardium occurred by day 7 after surgery. Clinical risk stratification in patients with surgically resectable micropapillary bladder cancer.

The Target

To analyse survival in patients with clinically localised, surgically resectable micropapillary bladder cancer MPBC undergoing radical cystectomy RC with and without neoadjuvant chemotherapy NAC and develop risk strata based on outcome data. Survival estimates were calculated using Kaplan-Meier method and compared using log-rank tests.

Intermediate-Risk Prostate Cancer Treatment - MUSC Hollings

Classification and regression tree CART analysis was performed to identify risk groups for survival. Patients with hydronephrosis do not appear to respond well to NAC and have poor prognosis regardless of treatment paradigm. However, further external validation studies are needed to support the proposed risk stratification before treatment recommendations can be made.

When dealing with skull base tumors that encase the internal carotid artery ICA , the surgeon must decide between ICA preservation and incomplete tumor resection , or radical resection with ICA sacrifice. In our experience with more than anterior skull base tumors, the ICA was sacrificed in only 10 patients.

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Full text of "Diseases of the bladder, prostate gland, and urethra"

These tumors were malignant, except for one meningioma that occluded the ICA and produced translent ischemic symptoms. This small patient series reflects our practice of preserving the ICA whenever possible. We recommend preserving the ICA with benign tumors because they do not invade the artery, or do so only to a limited extent. In addition, similar rates of tumor recurrence are seen after aggressive resection with or without ICA sacrifice. In contrast, we recommend radical tumor resection and sacrifice of the ICA with malignant tumors because they directly threaten the integrity of the ICA and the patient's survival.

The ICA should not be considered a limitation to radical tumor resection because the ICA can be reconstructed safely with an appropriate bypass procedure. The results of surgical treatment of patients, suffering differentiated cancer of the thyroid gland CTG and with medullar pathology were analyzed. In differentiated CTG the recurrence after performance of subtotal resection of the organ had occurred in The operation radicalism for differentiated CTG secures, as minimum, by application of thyroidectomy with central LN dissection.

For optimization of indications for dissection of lateral and mediastinal LN diagnostic lymphadenectomy is performed or the process stage is analyzed. While application of radical surgical tactics only during performance of subsequent for recurrence operations the essential lowering of calcitonin level is observed only in Surgical resection after TNFerade therapy for locally advanced pancreatic cancer. Treatment of pancreatic cancer remains a major oncological challenge and survival is dismal.